Statistical Inference in Systems Biology through Gaussian Processes and Ordinary Differential Equations


at Max Planck Society, Ringberg Castle, Germany on May 7, 2008 [pdf]
Neil D. Lawrence, University of Sheffield



In this talk we will summarise recent work from our group in Manchester on inferring ‘latent biochemical species’ in biological systems using Gaussian processes and differential equations. A key problem in biological data is when particular biochemical species of interest are not directly measurable. We will show how the framework of Gaussian processes can be brought to bear on the problem and values of latent chemical species can be inferred given data and a differential equation model.